Entrez ID
int64 47
103M
⌀ | Gene symbol
stringclasses 866
values | Gene name
stringclasses 866
values | Cancer Cell
stringclasses 2
values | Type of senescence
stringclasses 4
values | Senescence Effect
stringclasses 3
values | Reference
int64 1.56M
33.5M
⌀ |
|---|---|---|---|---|---|---|
22,848
|
AAK1
|
AP2 associated kinase 1
|
No
|
Unclear
|
Induces
| 26,583,757
|
5,243
|
ABCB1
|
ATP binding cassette subfamily B member 1
|
Yes
|
Stress-induced
|
Induces
| 10,825,123
|
368
|
ABCC6
|
ATP binding cassette subfamily C member 6
|
Yes
|
Unclear
|
Inhibits
| 28,536,638
|
51,225
|
ABI3
|
ABI family member 3
|
Yes
|
Oncogene-induced
|
Induces
| 21,223,585
|
25,890
|
ABI3BP
|
ABI family member 3 binding protein
|
Yes
|
Unclear
|
Induces
| 18,559,958
|
340,485
|
ACER2
|
alkaline ceramidase 2
|
Yes
|
Replicative
|
Inhibits
| 29,229,990
|
340,485
|
ACER2
|
alkaline ceramidase 2
|
Yes
|
Stress-induced
|
Inhibits
| 29,229,990
|
2,532
|
ACKR1
|
atypical chemokine receptor 1 (Duffy blood group)
|
No
|
Stress-induced
|
Induces
| 17,955,335
|
47
|
ACLY
|
ATP citrate lyase
|
No
|
Unclear
|
Inhibits
| 25,367,309
|
203,054
|
ADCK5
|
aarF domain containing kinase 5
|
No
|
Unclear
|
Induces
| 26,583,757
|
27,161
|
AGO2
|
argonaute RISC catalytic component 2
|
No
|
Oncogene-induced
|
Inhibits
| 25,175,024
|
10,551
|
AGR2
|
anterior gradient 2, protein disulphide isomerase family member
|
Yes
|
Oncogene-induced
|
Inhibits
| 22,467,239
|
183
|
AGT
|
angiotensinogen
|
No
|
Stress-induced
|
Induces
| 16,908,765
|
196
|
AHR
|
aryl hydrocarbon receptor
|
No
|
Stress-induced
|
Induces
| 15,111,621
|
8,852
|
AKAP4
|
A-kinase anchoring protein 4
|
Yes
|
Unclear
|
Inhibits
| 26,590,805
|
231
|
AKR1B1
|
aldo-keto reductase family 1 member B
|
Yes
|
Stress-induced
|
Inhibits
| 21,182,935
|
207
|
AKT1
|
AKT serine/threonine kinase 1
|
No
|
Oncogene-induced
|
Induces
| 17,045,205
|
84,335
|
AKT1S1
|
AKT1 substrate 1
|
Yes
|
Oncogene-induced
|
Inhibits
| 24,704,832
|
10,000
|
AKT3
|
AKT serine/threonine kinase 3
|
Yes
|
Stress-induced
|
Inhibits
| 26,972,278
|
64,400
|
AKTIP
|
AKT interacting protein
|
No
|
Replicative
|
Inhibits
| 27,512,140
|
217
|
ALDH2
|
aldehyde dehydrogenase 2 family member
|
No
|
Stress-induced
|
Inhibits
| 30,538,807
|
226
|
ALDOA
|
aldolase, fructose-bisphosphate A
|
Yes
|
Oncogene-induced
|
Inhibits
| 28,806,777
|
221,120
|
ALKBH3
|
alkB homolog 3, alpha-ketoglutarate dependent dioxygenase
|
Yes
|
Unclear
|
Inhibits
| 21,285,982
|
247
|
ALOX15B
|
arachidonate 15-lipoxygenase type B
|
No
|
Unclear
|
Induces
| 17,164,141
|
64,682
|
ANAPC1
|
anaphase promoting complex subunit 1
|
No
|
Unclear
|
Inhibits
| 25,255,445
|
54,443
|
ANLN
|
anillin actin binding protein
|
Yes
|
Unclear
|
Inhibits
| 27,863,473
|
308
|
ANXA5
|
annexin A5
|
No
|
Replicative
|
Inhibits
| 22,728,018
|
308
|
ANXA5
|
annexin A5
|
No
|
Stress-induced
|
Inhibits
| 22,728,018
|
328
|
APEX1
|
apurinic/apyrimidinic endodeoxyribonuclease 1
|
No
|
Replicative
|
Inhibits
| 29,750,271
|
367
|
AR
|
androgen receptor
|
No
|
Unclear
|
Induces
| 24,244,503
|
375
|
ARF1
|
ADP ribosylation factor 1
|
No
|
Oncogene-induced
|
Induces
| 29,420,297
|
384
|
ARG2
|
arginase 2
|
No
|
Unclear
|
Induces
| 23,832,324
|
384
|
ARG2
|
arginase 2
|
No
|
Unclear
|
Induces
| 22,928,666
|
8,289
|
ARID1A
|
AT-rich interaction domain 1A
|
No
|
Oncogene-induced
|
Induces
| 28,942,143
|
57,492
|
ARID1B
|
AT-rich interaction domain 1B
|
No
|
Oncogene-induced
|
Induces
| 27,737,960
|
1,820
|
ARID3A
|
AT-rich interaction domain 3A
|
No
|
Oncogene-induced
|
Inhibits
| 11,812,999
|
51,742
|
ARID4B
|
AT-rich interaction domain 4B
|
Yes
|
Oncogene-induced
|
Induces
| 16,479,010
|
10,095
|
ARPC1B
|
actin related protein 2/3 complex subunit 1B
|
Yes
|
Unclear
|
Induces
| 21,628,992
|
408
|
ARRB1
|
arrestin beta 1
|
Yes
|
Unclear
|
Induces
| 31,204,931
|
427
|
ASAH1
|
N-acylsphingosine amidohydrolase 1
|
Yes
|
Unclear
|
Inhibits
| 28,785,021
|
25,842
|
ASF1A
|
anti-silencing function 1A histone chaperone
|
No
|
Replicative
|
Induces
| 15,621,527
|
25,842
|
ASF1A
|
anti-silencing function 1A histone chaperone
|
No
|
Oncogene-induced
|
Induces
| 15,621,527
|
444
|
ASPH
|
aspartate beta-hydroxylase
|
Yes
|
Unclear
|
Inhibits
| 26,683,595
|
55,252
|
ASXL2
|
ASXL transcriptional regulator 2
|
No
|
Unclear
|
Induces
| 26,416,890
|
467
|
ATF3
|
activating transcription factor 3
|
Yes
|
Stress-induced
|
Inhibits
| 25,046,976
|
22,926
|
ATF6
|
activating transcription factor 6
|
No
|
Replicative
|
Induces
| 28,803,844
|
22,926
|
ATF6
|
activating transcription factor 6
|
No
|
Stress-induced
|
Induces
| 28,803,844
|
22,926
|
ATF6
|
activating transcription factor 6
|
No
|
Oncogene-induced
|
Induces
| 28,803,844
|
22,926
|
ATF6
|
activating transcription factor 6
|
No
|
Replicative
|
Induces
| 30,260,700
|
22,926
|
ATF6
|
activating transcription factor 6
|
No
|
Stress-induced
|
Induces
| 30,260,700
|
22,926
|
ATF6
|
activating transcription factor 6
|
No
|
Oncogene-induced
|
Induces
| 30,260,700
|
55,729
|
ATF7IP
|
activating transcription factor 7 interacting protein
|
No
|
Stress-induced
|
Inhibits
| 23,935,871
|
83,734
|
ATG10
|
autophagy related 10
|
Yes
|
Unclear
|
Induces
| 23,451,179
|
9,140
|
ATG12
|
autophagy related 12
|
No
|
Unclear
|
Inhibits
| 21,858,089
|
55,054
|
ATG16L1
|
autophagy related 16 like 1
|
Yes
|
Unclear
|
Unclear
| 22,684,298
|
84,971
|
ATG4D
|
autophagy related 4D cysteine peptidase
|
No
|
Unclear
|
Inhibits
| 30,352,807
|
9,474
|
ATG5
|
autophagy related 5
|
No
|
Oncogene-induced
|
Inhibits
| 19,279,323
|
10,533
|
ATG7
|
autophagy related 7
|
No
|
Oncogene-induced
|
Inhibits
| 19,279,323
|
472
|
ATM
|
ATM serine/threonine kinase
|
No
|
Replicative
|
Inhibits
| 9,312,059
|
23,545
|
ATP6V0A2
|
ATPase H+ transporting V0 subunit a2
|
No
|
Unclear
|
Inhibits
| 26,611,489
|
527
|
ATP6V0C
|
ATPase H+ transporting V0 subunit c
|
No
|
Unclear
|
Inhibits
| 30,352,807
|
545
|
ATR
|
ATR serine/threonine kinase
|
Yes
|
Oncogene-induced
|
Induces
| 18,245,444
|
51,374
|
ATRAID
|
all-trans retinoic acid induced differentiation factor
|
Yes
|
Unclear
|
Induces
| 26,934,949
|
546
|
ATRX
|
ATRX chromatin remodeler
|
Yes
|
Oncogene-induced
|
Induces
| 28,855,512
|
546
|
ATRX
|
ATRX chromatin remodeler
|
Yes
|
Stress-induced
|
Induces
| 28,855,512
|
25,814
|
ATXN10
|
ataxin 10
|
No
|
Unclear
|
Induces
| 21,740,549
|
6,790
|
AURKA
|
aurora kinase A
|
Yes
|
Unclear
|
Inhibits
| 23,324,396
|
9,212
|
AURKB
|
aurora kinase B
|
No
|
Unclear
|
Inhibits
| 22,024,481
|
558
|
AXL
|
AXL receptor tyrosine kinase
|
No
|
Unclear
|
Induces
| 26,583,757
|
9,531
|
BAG3
|
BAG cochaperone 3
|
Yes
|
Unclear
|
Inhibits
| 25,412,315
|
8,314
|
BAP1
|
BRCA1 associated protein 1
|
No
|
Unclear
|
Induces
| 26,416,890
|
11,177
|
BAZ1A
|
bromodomain adjacent to zinc finger domain 1A
|
Yes
|
Unclear
|
Inhibits
| 31,085,244
|
64,919
|
BCL11B
|
BAF chromatin remodeling complex subunit BCL11B
|
Yes
|
Unclear
|
Inhibits
| 26,096,706
|
596
|
BCL2
|
BCL2 apoptosis regulator
|
No
|
Oncogene-induced
|
Induces
| 12,670,482
|
598
|
BCL2L1
|
BCL2 like 1
|
Yes
|
Oncogene-induced
|
Inhibits
| 28,948,203
|
599
|
BCL2L2
|
BCL2 like 2
|
Yes
|
Oncogene-induced
|
Induces
| 30,318,121
|
602
|
BCL3
|
BCL3 transcription coactivator
|
No
|
Unclear
|
Inhibits
| 25,255,445
|
604
|
BCL6
|
BCL6 transcription repressor
|
No
|
Replicative
|
Inhibits
| 11,914,273
|
9,774
|
BCLAF1
|
BCL2 associated transcription factor 1
|
Yes
|
Stress-induced
|
Induces
| 26,794,446
|
8,678
|
BECN1
|
beclin 1
|
Yes
|
Unclear
|
Inhibits
| 29,991,800
|
8,553
|
BHLHE40
|
basic helix-loop-helix family member e40
|
Yes
|
Replicative
|
Induces
| 18,025,081
|
8,553
|
BHLHE40
|
basic helix-loop-helix family member e40
|
Yes
|
Stress-induced
|
Induces
| 18,025,081
|
8,553
|
BHLHE40
|
basic helix-loop-helix family member e40
|
Yes
|
Replicative
|
Induces
| 22,844,531
|
8,553
|
BHLHE40
|
basic helix-loop-helix family member e40
|
Yes
|
Stress-induced
|
Induces
| 22,844,531
|
274
|
BIN1
|
bridging integrator 1
|
No
|
Oncogene-induced
|
Induces
| 18,267,069
|
332
|
BIRC5
|
baculoviral IAP repeat containing 5
|
Yes
|
Oncogene-induced
|
Inhibits
| 27,531,889
|
640
|
BLK
|
BLK proto-oncogene, Src family tyrosine kinase
|
No
|
Unclear
|
Induces
| 26,583,757
|
644
|
BLVRA
|
biliverdin reductase A
|
No
|
Stress-induced
|
Inhibits
| 21,099,244
|
648
|
BMI1
|
BMI1 proto-oncogene, polycomb ring finger
|
No
|
Replicative
|
Inhibits
| 12,482,990
|
652
|
BMP4
|
bone morphogenetic protein 4
|
Yes
|
Replicative
|
Induces
| 19,269,967
|
652
|
BMP4
|
bone morphogenetic protein 4
|
Yes
|
Stress-induced
|
Induces
| 19,269,967
|
659
|
BMPR2
|
bone morphogenetic protein receptor type 2
|
Yes
|
Replicative
|
Induces
| 27,696,331
|
9,790
|
BMS1
|
BMS1 ribosome biogenesis factor
|
Yes
|
Replicative
|
Inhibits
| 25,732,822
|
9,790
|
BMS1
|
BMS1 ribosome biogenesis factor
|
Yes
|
Oncogene-induced
|
Inhibits
| 25,732,822
|
665
|
BNIP3L
|
BCL2 interacting protein 3 like
|
No
|
Oncogene-induced
|
Induces
| 18,267,069
|
673
|
BRAF
|
B-Raf proto-oncogene, serine/threonine kinase
|
No
|
Oncogene-induced
|
Induces
| 16,079,850
|
672
|
BRCA1
|
BRCA1 DNA repair associated
|
Yes
|
Stress-induced
|
Inhibits
| 19,372,557
|
23,476
|
BRD4
|
bromodomain containing 4
|
Yes
|
Unclear
|
Inhibits
| 29,434,197
|
29,117
|
BRD7
|
bromodomain containing 7
|
No
|
Replicative
|
Induces
| 20,660,729
|
83,990
|
BRIP1
|
BRCA1 interacting helicase 1
|
No
|
Oncogene-induced
|
Inhibits
| 22,137,763
|
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